52-vehicle Pile-up On A Highway A31, Emsland Autobahn, Germany

Major pileups
Date - Killed - Injured - Vehicles - Details
11 December 1990 - 12 - 42 - 99 - Interstate 75 in Calhoun, Tennessee, United States, between Chattanooga and Knoxville near the Hiwassee River, due to very heavy fog; fiery crash involved 99 vehicles; 12 deaths and 42 injuries. A fog warning system has since been installed, and the highway patrol enforces speed limits aggressively.